Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16574791 | 0.84 | BLM (0.47) | MEN1NOS3NOS1CYP2C19NOS2 | |
| SCHEMBL16920503 | 0.78 | LTA4H (0.46) | CA1NOS3NOS1NOS2BLM | |
| SCHEMBL16574757 | 0.78 | LTA4H (0.46) | CA1NOS3NOS1NOS2BLM | |
| SCHEMBL17551030 | 0.77 | — | — | |
| SCHEMBL12153331 | 0.75 | CA1 (0.48) | CA1BLM | |
| SCHEMBL15586875 | 0.73 | — | — | |
| SCHEMBL16574792 | 0.73 | — | — | |
| SCHEMBL15456968 | 0.73 | CA1 (0.34) | CA1MEN1CYP2C19KMT2ACNR2 | |
| SCHEMBL12153332 | 0.73 | CA1 (0.46) | CA1BLM | |
| SCHEMBL27809324 | 0.71 | GABRR1 (0.46) | BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170304420-A1 | POLYMER ADJUVANT | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304420-A1 | POLYMER ADJUVANT | TLR3, TLR9, TLR1 | CA1 2754/4885ALOX5 488/4885MEN1 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.