SCHEMBL19508089

SCHEMBL19508089

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5cc6c7ccccc7n(-c7ccc8ccccc8c7)c6cc54)c3)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPK10 P53779 3/20 0.37
MAPK9 P45984 2/20 0.37
HPGD P15428 1/20 0.36
RAC2 P15153 1/20 0.35
RAC3 P60763 1/20 0.35
CDC42 P60953 1/20 0.35
RAC1 P63000 1/20 0.35
ABCG2 Q9UNQ0 4/20 0.34
F2 P00734 1/20 0.34
F10 P00742 1/20 0.34
PRSS1 P07477 1/20 0.34
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.34
PLA2G10 O15496 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18088902 0.94 KDM4E (0.44) KDM4EATML3MBTL1HPGDABCG2
SCHEMBL22596073 0.93 KDM4E (0.40) KDM4EATML3MBTL1MAPK10MAPK9
SCHEMBL23568995 0.93 KDM4E (0.43) KDM4EATML3MBTL1MAPK10MAPK9
SCHEMBL22884170 0.93 KDM4E (0.41) KDM4EATML3MBTL1MAPK10MAPK9
SCHEMBL22595709 0.93 KDM4E (0.41) KDM4EATML3MBTL1MAPK10MAPK9
SCHEMBL23568831 0.93 ALDH1A1 (0.39) KDM4EATML3MBTL1MAPK10MAPK9
SCHEMBL12690813 0.92 L3MBTL1 (0.49) KDM4EATML3MBTL1HPGDABCG2
SCHEMBL23569607 0.92 KDM4E (0.39) KDM4EATML3MBTL1HPGDRAC2
SCHEMBL21022996 0.92 KDM4E (0.42) KDM4EATML3MBTL1MAPK10MAPK9
SCHEMBL23370366 0.92 CYP1A1 (0.40) KDM4EATML3MBTL1MAPK10MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041845-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-07-16 US disclosed
US-12041845-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-07-16 US disclosed
US-20220165969-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-05-26 US disclosed
US-20210343949-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-11-04 US disclosed
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME TORAY INDUSTRIES, INC. (JP) 2021-05-20 US disclosed
US-20200343450-A1 ORGANIC LIGHT-EMITTING DIODE LG CHEM, LTD. (KR) 2020-10-29 US disclosed
US-20190312218-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2019-10-10 US disclosed
US-20190259947-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2019-08-22 US disclosed
US-20190131542-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2019-05-02 US disclosed
WO-2018070773-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2018-04-19 WO disclosed
WO-2017183859-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12041845-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same L1CAM, OR10J3, EPCAM KDM4E 2182/4885ATM 2715/4885L3MBTL1 1380/4885
US-20220165969-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, EPCAM, L1CAM KDM4E 612/4885ATM 3210/4885L3MBTL1 834/4885
US-20190312218-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, EPCAM, L1CAM KDM4E 612/4885ATM 3210/4885L3MBTL1 834/4885
US-20200343450-A1 ORGANIC LIGHT-EMITTING DIODE NR2E3, LAS1L, CRY1 KDM4E 2212/4885ATM 2748/4885L3MBTL1 351/4885
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME CBR3, INTS9, CBR1 KDM4E 1196/4885ATM 2844/4885L3MBTL1 208/4885
US-20210343949-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, OR10J3, EPCAM KDM4E 2182/4885ATM 2715/4885L3MBTL1 1380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.