Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499044 | 0.81 | GAA (0.52) | HPGDHSD17B10TSHRKMT2APOLB | |
| SCHEMBL2163134 | 0.80 | MMP8 (0.50) | HPGDLMNAALDH1A1HSD17B10FKBP1A | |
| SCHEMBL2163129 | 0.80 | MMP8 (0.50) | HPGDLMNAALDH1A1HSD17B10FKBP1A | |
| SCHEMBL10454919 | 0.77 | KCNA5 (0.49) | LMNAALDH1A1HSD17B10FKBP1ATSHR | |
| SCHEMBL5421601 | 0.74 | FKBP1A (0.51) | HPGDALDH1A1FKBP1AKMT2ASMN1; SMN2 | |
| SCHEMBL5955863 | 0.74 | FKBP1A (0.51) | HPGDALDH1A1FKBP1AKMT2ASMN1; SMN2 | |
| SCHEMBL5955811 | 0.74 | FKBP1A (0.51) | HPGDALDH1A1FKBP1AKMT2ASMN1; SMN2 | |
| SCHEMBL5438934 | 0.73 | CTSS (0.57) | ALDH1A1KMT2ASMN1; SMN2POLBMEN1 | |
| SCHEMBL6649897 | 0.73 | KMT2A (0.51) | LMNAALDH1A1HSD17B10FKBP1ATSHR | |
| SCHEMBL3023913 | 0.73 | CTSS (0.57) | ALDH1A1KMT2ASMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158550-A9 | SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2017-10-26 | — | — | WO | disclosed |