Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19519452 | 0.91 | DGAT1 (0.36) | DGAT1IGLV6-57NR1H2NR1H3MAOB | |
| SCHEMBL3446635 | 0.87 | DGAT1 (0.40) | DGAT1NR1H2NR1H3MAOBMEN1 | |
| SCHEMBL20607798 | 0.82 | DGAT1 (0.48) | DGAT1MAOBMEN1KMT2AL3MBTL1 | |
| SCHEMBL19519743 | 0.79 | MAPT (0.37) | IGLV6-57MAOBSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13035523 | 0.78 | DGAT1 (0.43) | DGAT1MAOBMEN1KMT2AL3MBTL1 | |
| SCHEMBL3445787 | 0.77 | DGAT1 (0.40) | DGAT1MAOBMEN1KMT2AL3MBTL1 | |
| SCHEMBL1135226 | 0.76 | MAOB (0.46) | DGAT1MAOBMEN1KMT2ANPC1 | |
| SCHEMBL19777737 | 0.75 | DGAT1 (0.36) | DGAT1MAOB | |
| SCHEMBL1135188 | 0.74 | ERN1 (0.40) | MAOBKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1135235 | 0.73 | LIPG (0.36) | DGAT1LMNANPC1RAB9ALIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796735-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2017-10-24 | — | — | US | disclosed |