Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458191 | 0.84 | MAOB (0.40) | MAPTLMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL19519621 | 0.79 | DGAT1 (0.37) | IGLV6-57LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL14117442 | 0.76 | MAOB (0.56) | MAPTPOLBNPC1RAB9AERN1 | |
| SCHEMBL28055985 | 0.73 | ALDH1A3 (0.52) | LMNAALDH1A1HPGDHDAC8KMT2A | |
| SCHEMBL20995917 | 0.72 | TSHR (0.48) | MAPTLMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL13035521 | 0.72 | MAOB (0.44) | MAPTLMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL3445766 | 0.71 | MAOB (0.43) | MAPTLMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL1134308 | 0.70 | MAOB (0.56) | MAPTPOLBNPC1RAB9AERN1 | |
| SCHEMBL17049557 | 0.69 | PSMB5 (0.48) | MAPTALDH1A1MEN1KMT2ASLC1A3 | |
| SCHEMBL19647535 | 0.69 | MAPT (0.36) | MAPTLMNAL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796735-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2017-10-24 | — | — | US | disclosed |