Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066692 | 0.89 | HTT (0.39) | HTTTDP1L3MBTL1FDFT1SMN1; SMN2 | |
| SCHEMBL10033513 | 0.86 | ALDH1A1 (0.41) | HTTTDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL14454544 | 0.85 | CA1 (0.45) | SMN1; SMN2POLBHSD11B1LMNAMAPT | |
| SCHEMBL12464120 | 0.82 | HTT (0.40) | HTTTDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL13243767 | 0.81 | HSD11B1 (0.37) | HTTTDP1L3MBTL1FDFT1SMN1; SMN2 | |
| SCHEMBL12608146 | 0.81 | NPC1 (0.45) | HTTTDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL10066693 | 0.80 | NPC1 (0.53) | HTTTDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL10709703 | 0.80 | HTT (0.60) | HTTTDP1L3MBTL1FDFT1SMN1; SMN2 | |
| SCHEMBL18801605 | 0.79 | HTT (0.67) | HTTTDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL10000946 | 0.79 | ALDH1A1 (0.57) | HTTTDP1L3MBTL1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748227-B1 | POLYSULFONE COMPOSITIONS AND METHODS FOR THE MANUFACTURE AND USE THEREOF | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2017-11-01 | — | — | EP | disclosed |