SCHEMBL1952956

SCHEMBL1952956

CCOCc1nc2c(N)nc3ccccc3c2n1CCCN

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 11/20 0.80
TLR7 Q9NYK1 19/20 0.71
NUDT1 P36639 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30954539 1.00 TLR8 (0.80) TLR8TLR7NUDT1
SCHEMBL2744543 0.97 TLR8 (0.79) TLR8TLR7NUDT1
SCHEMBL29381767 0.97 TLR8 (0.79) TLR8TLR7NUDT1
SCHEMBL6098914 0.93 TLR8 (0.77) TLR8TLR7NUDT1
SCHEMBL1616206 0.93 TLR8 (0.84) TLR8TLR7NUDT1
SCHEMBL20467576 0.93 TLR8 (0.80) TLR8TLR7NUDT1
SCHEMBL3868221 0.92 TLR8 (0.75) TLR8TLR7NUDT1
Hydrochloric Acid SCHEMBL3863644 0.92 TLR8 (0.82) TLR8TLR7NUDT1
Hydrochloric Acid SCHEMBL6493853 0.92 TLR8 (0.82) TLR8TLR7NUDT1
SCHEMBL1952959 0.91 TLR8 (0.71) TLR8TLR7NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665402-A1 COPOLYMER-DRUG CONJUGATE FOR TREATMENT OF TUMOURS Danmarks Tekniske Universitet (DK) 2025-12-24 EP claimed
WO-2024170742-A1 COPOLYMER-DRUG CONJUGATE FOR TREATMENT OF TUMOURS DANMARKS TEKNISKE UNIVERSITET (DK) 2024-08-22 WO claimed
EP-4665402-A1 COPOLYMER-DRUG CONJUGATE FOR TREATMENT OF TUMOURS Danmarks Tekniske Universitet (DK) 2025-12-24 EP disclosed
WO-2024170742-A1 COPOLYMER-DRUG CONJUGATE FOR TREATMENT OF TUMOURS DANMARKS TEKNISKE UNIVERSITET (DK) 2024-08-22 WO disclosed
EP-3344622-B1 GUANIDINE SUBSTITUTED, FUSED 1H-IMIDAZO[4,5-C]PYRIDINE COMPOUNDS USEFUL IN THE TREATMENT OF VIRAL AND NEOPLASTIC DISEASES 3M INNOVATIVE PROPERTIES CO (US) 2021-07-07 EP disclosed
US-10487081-B2 Guanidine substituted imidazo[4,5-c] ring compounds 3M INNOVATION PROPERTIES COMPANY (US) 2019-11-26 US disclosed
US-20190055241-A1 GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2019-02-21 US disclosed
US-10150768-B2 Guanidine substituted imidazo[4,5-c] ring compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-12-11 US disclosed
US-20180237435-A1 GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2018-08-23 US disclosed
EP-3344622-A1 GUANIDINE SUBSTITUTED IMIDAZO[4,5-c]RING COMPOUNDS 3M Innovative Properties Company (US) 2018-07-11 EP disclosed
US-9962453-B2 Immunogenic compound ALTIMMUNE UK LIMITED (GB) 2018-05-08 US disclosed
EP-1638566-A2 SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2006-03-29 EP disclosed
US-20050197358-A1 Sulfonamide and sulfamide substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2005-09-08 US disclosed
US-6924293-B2 Sulfonamide and sulfamide substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-08-02 US disclosed
US-6888000-B2 Sulfonamide and sulfamide substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-05-03 US disclosed
WO-2005003064-A2 SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-01-13 WO disclosed
WO-2005003065-A2 SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-01-13 WO disclosed
US-20040132762-A1 Sulfonamide and sulfamide substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2004-07-08 US disclosed
US-20040106638-A1 Sulfonamide and sulfamide substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2004-06-03 US disclosed
US-6677349-B1 INDUCE CYTOKINE BIOSYNTHESIS; ANTICARCINOGENIC AGENTS, VIRICIDES 3M INNOVATIVE PROPERTIES COMPANY 2004-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050197358-A1 Sulfonamide and sulfamide substituted imidazoquinolines IFNG, IRF3, EIF2AK2 TLR8 71/4885TLR7 59/4885NUDT1 1569/4885
US-10150768-B2 Guanidine substituted imidazo[4,5-c] ring compounds IFNG, IL4, IRF3 TLR8 163/4885TLR7 55/4885NUDT1 260/4885
US-10487081-B2 Guanidine substituted imidazo[4,5-c] ring compounds IFNG, IRF3, IL4 TLR8 211/4885TLR7 63/4885NUDT1 337/4885
US-20040132762-A1 Sulfonamide and sulfamide substituted imidazoquinolines IFNG, IRF3, EIF2AK2 TLR8 71/4885TLR7 59/4885NUDT1 1569/4885
US-20190055241-A1 GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS IFNG, IRF3, IL4 TLR8 211/4885TLR7 63/4885NUDT1 337/4885
US-20180237435-A1 GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS IFNG, IL4, IRF3 TLR8 163/4885TLR7 55/4885NUDT1 260/4885
US-20040106638-A1 Sulfonamide and sulfamide substituted imidazoquinolines IFNG, IRF3, EIF2AK2 TLR8 71/4885TLR7 59/4885NUDT1 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.