Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 6/20 | 0.62 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1953367 | 1.00 | EEF2K (0.62) | EEF2KKCNA5ITGB3ITGA2BMCHR1 | |
| SCHEMBL1951815 | 0.91 | EEF2K (0.52) | EEF2KKCNA5MCHR1MAPTALDH1A1 | |
| SCHEMBL1951814 | 0.91 | EEF2K (0.52) | EEF2KKCNA5MCHR1MAPTALDH1A1 | |
| SCHEMBL12550689 | 0.90 | EEF2K (0.51) | EEF2KKCNA5MAPTALDH1A1POLB | |
| SCHEMBL12550340 | 0.88 | EEF2K (0.48) | EEF2KKCNA5MAPTALDH1A1POLB | |
| SCHEMBL16622577 | 0.88 | EEF2K (0.48) | EEF2KKCNA5MAPTALDH1A1POLB | |
| SCHEMBL12551122 | 0.88 | ITGB3 (0.46) | EEF2KITGB3ITGA2BALDH1A1POLB | |
| SCHEMBL12550399 | 0.88 | EEF2K (0.48) | EEF2KKCNA5MAPTALDH1A1POLB | |
| SCHEMBL14754777 | 0.86 | EEF2K (0.47) | EEF2KKCNA5MAPTALDH1A1POLB | |
| SCHEMBL1955101 | 0.86 | EEF2K (0.47) | EEF2KKCNA5MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507210-B1 | CYCLOHEXANE DERIVATIVES AS INHIBITORS OF ACETYL-COA CARBOXYLASE (ACC) | NOVARTIS AG (CH) | 2015-04-08 | — | — | EP | disclosed |
| US-8394858-B2 | Cyclohexane derivatives and uses thereof | NOVARTIS AG (CH) | 2013-03-12 | — | — | US | disclosed |
| US-20110136735-A1 | CYCLOHEXANE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136735-A1 | CYCLOHEXANE DERIVATIVES AND USES THEREOF | CYP3A5, CYP11B2, CNR2 | EEF2K 2215/4885KCNA5 1186/4885ITGB3 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.