Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10969375 | 0.81 | ALDH1A1 (0.64) | KDM4EALDH1A1RAB9ACHKALMNA | |
| SCHEMBL25459980 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1RAB9ACHKALMNA | |
| Hydrochloric Acid SCHEMBL7166354 | 0.80 | ALDH1A1 (0.66) | KDM4EALDH1A1RAB9AGSK3BCHKA | |
| SCHEMBL1108034 | 0.80 | ALDH1A1 (0.66) | KDM4EALDH1A1RAB9AGSK3BCHKA | |
| Hydrochloric Acid SCHEMBL28357009 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1RAB9AGSK3BCHKA | |
| Hydrochloric Acid SCHEMBL27637987 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1RAB9AGSK3BCHKA | |
| SCHEMBL19646819 | 0.76 | CHKA (0.49) | KDM4EALDH1A1RAB9ACYP17A1CYP11B1 | |
| SCHEMBL13561376 | 0.75 | CHKA (0.53) | KDM4EALDH1A1RAB9ACHKALMNA | |
| SCHEMBL1108062 | 0.74 | ALDH1A1 (0.62) | KDM4EALDH1A1RAB9AGSK3BCHKA | |
| Bromide SCHEMBL15361681 | 0.73 | CHKA (0.55) | KDM4EALDH1A1RAB9ACHKALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9810962-B1 | Electrochromic material and anti-dazzle mirror having the same | E-CHEM ENTERPRISE CORP. (TW) | 2017-11-07 | — | — | US | disclosed |