Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15160536 | 0.95 | ALDH1A1 (0.44) | HPGDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3526817 | 0.76 | HPGD (0.39) | HPGDALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL27735108 | 0.75 | HPGD (0.39) | HPGDALDH1A1MEN1LMNAHTT | |
| SCHEMBL25406327 | 0.74 | GSK3B (0.39) | L3MBTL1POLBAPEX1RECQLTDP1 | |
| SCHEMBL12862571 | 0.74 | HRH3 (0.41) | HPGDALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL25406325 | 0.74 | GSK3B (0.39) | L3MBTL1POLBAPEX1RECQLTDP1 | |
| SCHEMBL3004757 | 0.74 | L3MBTL1 (0.55) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9900364 | 0.72 | ALDH1A1 (0.49) | HPGDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10136902 | 0.72 | ALDH1A1 (0.49) | HPGDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11983577 | 0.72 | HPGD (0.44) | HPGDALDH1A1HTTTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017189613-A1 | METHODS OF USING FASN INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2017-11-02 | — | — | WO | disclosed |
| CN-104059066-A | Diazacarbazoles And Methods Of Use | GENENTECH INC | 2014-09-24 | — | — | CN | disclosed |
| CN-102119163-A | Diazacarbazoles and methods of use | GENENTECH INC | 2011-07-06 | — | — | CN | disclosed |