Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25406327 | 1.00 | GSK3B (0.39) | GSK3BCHRM2CHRM1CHRM3HTR2C | |
| SCHEMBL3016545 | 0.76 | SLC6A2 (0.46) | CHRM2CHRM1CHRM3HTR2CHTR2A | |
| SCHEMBL15160536 | 0.76 | ALDH1A1 (0.44) | NPC1RAB9APOLBAPEX1RECQL | |
| SCHEMBL19540314 | 0.74 | HPGD (0.50) | NPC1RAB9APOLBAPEX1RECQL | |
| SCHEMBL5797267 | 0.73 | HTR2C (0.48) | GSK3BHTR2CHTR2AHTR2BLATS1 | |
| SCHEMBL3015463 | 0.73 | SLC6A4 (0.61) | HTR2CHTR2AHTR2B | |
| SCHEMBL11199899 | 0.73 | L3MBTL1 (0.37) | HTR2CHTR2AHTR2BL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2892940 | 0.72 | KDM4E (0.50) | GSK3BHTR2CHTR2AHTR2BLATS1 | |
| Hydrochloric Acid SCHEMBL16235859 | 0.72 | KDM4E (0.50) | GSK3BHTR2CHTR2AHTR2BLATS1 | |
| SCHEMBL5371831 | 0.72 | HTR2C (0.41) | GSK3BHTR2CHTR2AHTR2BLATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851435-B2 | PTGR2 inhibitors and their use | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2023-12-26 | — | — | US | disclosed |
| US-20230279008-A1 | PTGR2 INHIBITORS AND THEIR USE | NATIONAL TAIWAN UNIVERSITY (TW) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851435-B2 | PTGR2 inhibitors and their use | PTGFR, PTGIR, PTGDR2 | GSK3B 2581/4885CHRM2 468/4885CHRM1 648/4885 |
| US-20230279008-A1 | PTGR2 INHIBITORS AND THEIR USE | PTGFR, PTGIR, PTGDR2 | GSK3B 2581/4885CHRM2 468/4885CHRM1 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.