SCHEMBL19543732

SCHEMBL19543732

Cc1cc(C)nc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 0.58
KMT2A Q03164 10/20 0.58
MAPT P10636 8/20 0.58
HPGD P15428 7/20 0.58
ALDH1A1 P00352 5/20 0.58
NTSR1 P30989 1/20 0.53
L3MBTL1 Q9Y468 3/20 0.52
LMNA P02545 3/20 0.51
KDM4E B2RXH2 5/20 0.50
ADORA2A P29274 1/20 0.50
ADORA1 P30542 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
GLA P06280 1/20 0.50
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
CYP2C19 P33261 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
GBA1 P04062 1/20 0.46
MAPK1 P28482 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3848271 0.91 KMT2A (0.53) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL19037222 0.88 MEN1 (0.49) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL13203382 0.86 MEN1 (0.54) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL18325407 0.84 MEN1 (0.56) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL18325417 0.84 MEN1 (0.56) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL19164654 0.84 MEN1 (0.61) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL19164369 0.84 MEN1 (0.61) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL25491455 0.83 LMNA (0.61) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL16922505 0.83 LMNA (0.61) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL16373471 0.83 LMNA (0.61) MEN1KMT2AMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11329230-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 US disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11329230-B2 Organic light-emitting device EML4, SUN2, TRPA1 MEN1 2816/4885KMT2A 1971/4885MAPT 735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.