SCHEMBL19543796

SCHEMBL19543796

CO[Si](CCC[Si](C)(C)OC[SiH](C)C)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1887028 0.75 LMNA (0.39) LMNA
SCHEMBL30112923 0.75 LMNA (0.33) LMNA
SCHEMBL329127 0.72 LMNA (0.46) LMNA
SCHEMBL30112945 0.71 LMNA (0.39) LMNA
SCHEMBL164465 0.70 LMNA (0.35) LMNA
SCHEMBL28593741 0.69 LMNA (0.36) LMNA
SCHEMBL5831600 0.69 LMNA (0.38) LMNA
SCHEMBL12678063 0.69 LMNA (0.42) LMNA
SCHEMBL12377361 0.69 LMNA (0.42) LMNA
SCHEMBL14984862 0.68 LMNA (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170313728-A1 TRANSPARENT FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170313728-A1 TRANSPARENT FILM TLL1, MGLL, LIPA LMNA 480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.