Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544299 | 0.84 | HPGD (0.46) | HPGDKDM4EL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL19544473 | 0.77 | SCN9A (0.51) | HPGDKDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19544636 | 0.76 | KDM4E (0.39) | HPGDKDM4EL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL19544302 | 0.73 | ALPL (0.63) | HPGDKDM4EL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL19544896 | 0.72 | NPSR1 (0.42) | HPGDKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL19545219 | 0.71 | MAPT (0.47) | HPGDKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL5937229 | 0.71 | ALDH1A1 (0.53) | HPGDKDM4EL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL19544753 | 0.70 | HPGDS (0.46) | HPGDKDM4EL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL1456158 | 0.70 | KMT2A (0.53) | HPGDKDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25060355 | 0.70 | BTK (0.48) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662174-B2 | BTK inhibitor | HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-20170313683-A1 | BTK INHIBITOR | HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662174-B2 | BTK inhibitor | BTK, SYK, LYN | HPGD 4511/4885KDM4E 898/4885L3MBTL1 2099/4885 |
| US-20170313683-A1 | BTK INHIBITOR | BTK, SYK, LYN | HPGD 4511/4885KDM4E 898/4885L3MBTL1 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.