Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 18/20 | 0.41 |
| ▸ | JAK2 | O60674 | 10/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828299 | 0.87 | NTRK1 (0.40) | NTRK1JAK2OPRM1 | |
| SCHEMBL28796117 | 0.84 | NTRK1 (0.45) | NTRK1JAK2OPRM1 | |
| SCHEMBL19547178 | 0.79 | RIPK1 (0.33) | OPRM1 | |
| SCHEMBL28828213 | 0.79 | NTRK1 (0.41) | NTRK1JAK2 | |
| SCHEMBL28828267 | 0.79 | NTRK1 (0.41) | NTRK1JAK2 | |
| SCHEMBL28950329 | 0.79 | NTRK1 (0.42) | NTRK1JAK2OPRM1 | |
| SCHEMBL16474196 | 0.79 | NTRK1 (0.43) | NTRK1JAK2OPRM1 | |
| SCHEMBL19547185 | 0.78 | NTRK1 (0.46) | NTRK1JAK2 | |
| SCHEMBL28263439 | 0.77 | NTRK1 (0.43) | NTRK1JAK2 | |
| SCHEMBL28682432 | 0.77 | NTRK1 (0.44) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945378-A | Feeder-layer and feeder-layer-free stem cell culture systems for stratified epithelial stem cells and uses related thereto | 休斯敦大学体系 | 2022-08-26 | — | — | CN | disclosed |
| EP-2791139-B1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AS TROPOMYOSIN RECEPTOR KINASE A (TRKA) INHIBITORS | Dr Reddys Laboratories Ltd (IN) | 2017-11-08 | — | — | EP | disclosed |