Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 10/20 | 0.60 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435574 | 0.79 | IMPDH2 (0.64) | SLC22A12IMPDH2IMPDH1MAPT | |
| SCHEMBL17899873 | 0.75 | SLC22A12 (1.00) | SLC22A12IMPDH2IMPDH1 | |
| SCHEMBL19435545 | 0.73 | SLC22A12 (0.57) | SLC22A12IMPDH2IMPDH1MAPT | |
| SCHEMBL19435497 | 0.72 | SLC22A12 (0.54) | SLC22A12IMPDH2IMPDH1MAPTLMNA | |
| SCHEMBL28387500 | 0.71 | SLC22A12 (0.42) | SLC22A12IMPDH2IMPDH1MAPTNCEH1 | |
| SCHEMBL28388335 | 0.70 | SLC22A12 (0.41) | SLC22A12IMPDH2IMPDH1 | |
| SCHEMBL19435572 | 0.69 | SLC22A12 (0.51) | SLC22A12IMPDH2IMPDH1LMNA | |
| SCHEMBL17899864 | 0.69 | SLC22A12 (0.75) | SLC22A12IMPDH2IMPDH1MAPT | |
| SCHEMBL19562895 | 0.66 | SLC22A12 (0.48) | SLC22A12IMPDH2IMPDH1 | |
| SCHEMBL22065338 | 0.66 | SLC22A12 (0.48) | SLC22A12MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3241822-B1 | URAT1 INHIBITOR | NIPPON CHEMIPHAR CO (JP) | 2021-03-24 | — | — | EP | disclosed |
| EP-3241822-A1 | URAT1 INHIBITOR | Nippon Chemiphar Co., Ltd. (JP) | 2017-11-08 | — | — | EP | disclosed |