Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384020 | 0.79 | IMPDH2 (0.51) | SLC22A12MCL1CA1CA2KDM4E | |
| SCHEMBL28063135 | 0.74 | MCL1 (0.46) | SLC22A12MCL1GSK3BADKCA1 | |
| SCHEMBL28383517 | 0.73 | SLC22A12 (0.46) | SLC22A12MCL1GSK3BADKCA1 | |
| SCHEMBL9493355 | 0.72 | GAA (0.44) | KDM4EIMPDH2IMPDH1ALDH1A1GAA | |
| SCHEMBL19547904 | 0.71 | SLC22A12 (0.60) | SLC22A12IMPDH2IMPDH1MAPTNCEH1 | |
| SCHEMBL28388485 | 0.71 | MCL1 (0.46) | SLC22A12MCL1CA1CA2KDM4E | |
| SCHEMBL28388335 | 0.70 | SLC22A12 (0.41) | SLC22A12IMPDH2IMPDH1 | |
| SCHEMBL11908319 | 0.70 | MAPT (0.53) | MAPTRAB9ANCEH1 | |
| SCHEMBL15223488 | 0.70 | NCEH1 (0.45) | KDM4EALDH1A1MAPTHPGDNCEH1 | |
| SCHEMBL28394409 | 0.70 | SLC22A12 (0.44) | SLC22A12CA1CA2MAPTNCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108478-B | URAT1 inhibitors | 日本化学药品株式会社 | 2020-04-24 | — | — | CN | disclosed |