Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694289 | 0.95 | FTO (0.46) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL8215926 | 0.84 | FTO (0.49) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL284851 | 0.82 | MAPT (0.65) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL273427 | 0.79 | FTO (0.59) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL1030138 | 0.79 | MAPT (0.67) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL4632262 | 0.78 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL8207575 | 0.78 | FTO (0.50) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL9474742 | 0.78 | FTO (0.58) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL9301961 | 0.78 | FTO (0.46) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL1703820 | 0.78 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370351-B2 | Photoinduced electron transfer voltage-sensitive compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-08-06 | — | — | US | disclosed |
| US-20170320846-A1 | PHOTOINDUCED ELECTRON TRANSFER VOLTAGE-SENSITIVE COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370351-B2 | Photoinduced electron transfer voltage-sensitive compounds | VDAC1, VDAC3, VDAC2 | MEN1 3178/4885KMT2A 3225/4885MAPT 1409/4885 |
| US-20170320846-A1 | PHOTOINDUCED ELECTRON TRANSFER VOLTAGE-SENSITIVE COMPOUNDS | VDAC1, VDAC3, VDAC2 | MEN1 3178/4885KMT2A 3225/4885MAPT 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.