Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450225 | 0.85 | GAA (0.56) | LMNAGAAAKR1B1ACP3TAAR1 | |
| SCHEMBL7527885 | 0.81 | LMNA (0.55) | LMNAGAAAKR1B1ACP3TAAR1 | |
| SCHEMBL1958962 | 0.81 | KIF11 (0.51) | TAAR1MIFIDO1KMT2ADAO | |
| SCHEMBL10494329 | 0.79 | GALR3 (0.53) | LMNAGAAAKR1B1ACP3TAAR1 | |
| SCHEMBL10494334 | 0.78 | AKR1B1 (0.44) | LMNAGAAAKR1B1ACP3TAAR1 | |
| SCHEMBL497366 | 0.77 | ACP3 (0.57) | LMNAGAAAKR1B1ACP3TAAR1 | |
| SCHEMBL14426935 | 0.77 | LMNA (0.52) | LMNAGAAAKR1B1ACP3TAAR1 | |
| SCHEMBL10478553 | 0.76 | AKR1B1 (0.43) | LMNAGAAAKR1B1ACP3TAAR1 | |
| SCHEMBL2377114 | 0.76 | HTR2A (0.53) | LMNAGAAAKR1B1ACP3TAAR1 | |
| SCHEMBL4879814 | 0.76 | KIF11 (0.57) | LMNAGAAAKR1B1ACP3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507209-B1 | PESTICIDAL BIS-ORGANOSULFUR COMPOUNDS | MERIAL INC (US) | 2015-07-08 | — | — | EP | disclosed |
| CN-102712583-B | Pesticidal bis-organosulfur compounds | MERIAL LTD | 2015-04-08 | — | — | CN | disclosed |
| US-8846569-B2 | Pesticidal bis-organosulfur compounds | MERIAL LIMITED (US) | 2014-09-30 | — | — | US | disclosed |
| US-20120283094-A1 | PESTICIDAL BIS-ORGANOSULFUR COMPOUNDS | MERIAL, INC. | 2012-11-08 | — | — | US | disclosed |
| EP-2507209-A1 | PESTICIDAL BIS-ORGANOSULFUR COMPOUNDS | Merial Limited (US) | 2012-10-10 | — | — | EP | disclosed |
| CN-102712583-A | Pesticidal bis-organosulfur compounds | MERIAL LTD | 2012-10-03 | — | — | CN | disclosed |
| WO-2011069143-A1 | PESTICIDAL BIS-ORGANOSULFUR COMPOUNDS | MERIAL LIMITED (US) | 2011-06-09 | — | — | WO | disclosed |
| US-5886195-A | REACTING AN APPROPRIATE CARBOXALDEHYDE WITH AN APPROPRIATE SULFONYLACETONITRILE | SUGEN, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5710173-A | ANTITUMOR AGENTS OR ANTICARCINOGENIC AGENTS | SUGEN, INC. (US) | 1998-01-20 | — | — | US | disclosed |
| WO-1996040675-A1 | THIENYL COMPOUNDS FOR INHIBITION OF CELL PROLIFERATIVE DISORDERS | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283094-A1 | PESTICIDAL BIS-ORGANOSULFUR COMPOUNDS | DDT, GSS, GSR | LMNA 4134/4885GAA 3408/4885AKR1B1 2649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.