Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 8/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.44 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19575809 | 0.89 | KCNK2 (0.42) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554190 | 0.89 | KMT2A (0.49) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554218 | 0.86 | MEN1 (0.47) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554231 | 0.86 | KMT2A (0.50) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554266 | 0.86 | KMT2A (0.55) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554226 | 0.84 | KCNK2 (0.42) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554236 | 0.84 | SERPINE1 (0.46) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554188 | 0.83 | F11 (0.47) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19570245 | 0.83 | NPC1 (0.49) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554253 | 0.83 | F11 (0.46) | MEN1PKMKMT2ANPSR1SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |