Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554253 | 0.90 | F11 (0.46) | F11MEN1PKMKMT2ANPSR1 | |
| SCHEMBL19554266 | 0.89 | KMT2A (0.55) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554263 | 0.87 | MEN1 (0.51) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19570245 | 0.86 | NPC1 (0.49) | F11MEN1PKMKMT2ANPSR1 | |
| SCHEMBL19554190 | 0.83 | KMT2A (0.49) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554136 | 0.83 | MEN1 (0.48) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554246 | 0.82 | PDE4B (0.44) | F11MEN1PKMKMT2ANPSR1 | |
| SCHEMBL19554171 | 0.82 | PDE5A (0.48) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554231 | 0.81 | KMT2A (0.50) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554218 | 0.81 | MEN1 (0.47) | MEN1PKMKMT2ANPSR1SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |