Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.66 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.54 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 2/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352338 | 0.88 | KMT2A (0.57) | DHODHMEN1KMT2AALBF2 | |
| SCHEMBL6352642 | 0.86 | KCNK2 (0.60) | DHODHAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL19554335 | 0.86 | ALB (0.51) | DHODHMEN1KMT2AMAPTTDP1 | |
| SCHEMBL19554161 | 0.86 | CA2 (0.56) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6359401 | 0.83 | ALB (0.63) | MEN1KMT2AMAPTTDP1ALB | |
| SCHEMBL6351365 | 0.83 | AKR1C2 (0.70) | DHODHAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL19554348 | 0.83 | ALB (0.48) | DHODHAKR1C2AKR1C1MEN1KMT2A | |
| SCHEMBL19554148 | 0.81 | DHODH (0.70) | DHODHAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6357745 | 0.81 | DHODH (0.78) | DHODHAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6346687 | 0.81 | ALB (0.60) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |