Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.48 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 8/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352338 | 0.85 | KMT2A (0.57) | ALBNR1H4DHODHPLAUF2 | |
| SCHEMBL19554146 | 0.83 | DHODH (0.66) | ALBDHODHAKR1C2AKR1C1PLAU | |
| SCHEMBL19554335 | 0.83 | ALB (0.51) | ALBDHODHPLAUF2PLG | |
| SCHEMBL19554161 | 0.83 | CA2 (0.56) | ALBAKR1C2AKR1C1MEN1KMT2A | |
| SCHEMBL6359036 | 0.81 | MEN1 (0.66) | ALBPLK1PLK3AKR1C2AKR1C1 | |
| SCHEMBL6359401 | 0.80 | ALB (0.63) | ALBLTC4SPLAUF2PLG | |
| SCHEMBL6919844 | 0.80 | PLK1 (0.71) | PLK1PLK3 | |
| SCHEMBL19554170 | 0.79 | F2 (0.47) | LTC4SPLK1PLK3NR1H4DHODH | |
| SCHEMBL19554175 | 0.79 | F2 (0.47) | LTC4SPLK1PLK3NR1H4DHODH | |
| SCHEMBL6355568 | 0.79 | PLK1 (0.63) | ALBPLK1PLK3NR1H4AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |