Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | PRSS12 | P56730 | 3/20 | 0.44 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.43 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554312 | 0.90 | KMT2A (0.48) | MEN1PKMKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL19554201 | 0.84 | SERPINE1 (0.59) | MEN1PKMKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL19554253 | 0.84 | F11 (0.46) | MEN1PKMKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL19554111 | 0.83 | KMT2A (0.58) | MEN1PKMKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL19554337 | 0.78 | AKR1C4 (0.54) | MEN1KMT2ASMN1; SMN2AKR1C4AKR1C3 | |
| SCHEMBL19554134 | 0.78 | SERPINE1 (0.68) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554263 | 0.77 | MEN1 (0.51) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554300 | 0.76 | MAPT (0.56) | MEN1PKMKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL19554283 | 0.76 | KDM4E (0.60) | MEN1PKMKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL19554229 | 0.75 | SERPINE1 (0.61) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |