Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 11/20 | 0.61 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.58 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554134 | 0.91 | SERPINE1 (0.68) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554260 | 0.85 | DHODH (0.67) | AKR1C4AKR1C3AKR1C2AKR1C1KCNK2 | |
| SCHEMBL19554148 | 0.85 | DHODH (0.70) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554129 | 0.84 | SERPINE1 (0.66) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554330 | 0.84 | KCNK2 (0.46) | KCNK2KCNK10 | |
| SCHEMBL19554240 | 0.84 | STING1 (0.50) | KCNK2KDM4E | |
| SCHEMBL19554150 | 0.83 | KCNK2 (0.52) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554123 | 0.83 | KCNK2 (0.50) | AKR1C2AKR1C1KCNK2KCNK10 | |
| SCHEMBL19575738 | 0.83 | TAS1R3 (0.45) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19575815 | 0.82 | F10 (0.44) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |