Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554290 | 0.89 | SMN1; SMN2 (0.47) | MEN1KMT2ANPSR1PKMALDH1A1 | |
| SCHEMBL19554283 | 0.88 | KDM4E (0.60) | MEN1KMT2ANPSR1PKMSERPINE1 | |
| SCHEMBL19554188 | 0.87 | F11 (0.47) | MEN1KMT2ANPSR1PKMSERPINE1 | |
| SCHEMBL19554111 | 0.79 | KMT2A (0.58) | MEN1KMT2ANPSR1PKMSERPINE1 | |
| SCHEMBL19554288 | 0.79 | KMT2A (0.55) | MEN1KMT2ANPSR1PKMALDH1A1 | |
| SCHEMBL19554300 | 0.79 | MAPT (0.56) | MEN1KMT2ANPSR1PKMALDH1A1 | |
| SCHEMBL19554221 | 0.79 | KMT2A (0.64) | MEN1KMT2ANPSR1PKMALDH1A1 | |
| SCHEMBL19554134 | 0.78 | SERPINE1 (0.68) | SERPINE1KDM4EAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL19554243 | 0.78 | KMT2A (0.57) | MEN1KMT2ANPSR1PKMALDH1A1 | |
| SCHEMBL19554152 | 0.77 | MEN1 (0.47) | MEN1KMT2ANPSR1PKMSERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |