Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | SERPINE1 | P05121 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554141 | 0.87 | ACLY (0.52) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554150 | 0.87 | KCNK2 (0.52) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554163 | 0.85 | SERPINE1 (0.60) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554134 | 0.77 | SERPINE1 (0.68) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554183 | 0.76 | SERPINE1 (0.52) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554247 | 0.76 | SERPINE1 (0.57) | SERPINE1MEN1KMT2AAKR1C4AKR1C3 | |
| SCHEMBL10473057 | 0.75 | MGAM (0.62) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL17294255 | 0.73 | PLK1 (0.50) | PPARGPPARAMEN1KMT2AGFER | |
| SCHEMBL420631 | 0.72 | SERPINE1 (0.82) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19575630 | 0.72 | HDAC3 (0.46) | SERPINE1KCNK2KCNK10F10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |