Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNK10 | P57789 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554330 | 0.86 | KCNK2 (0.46) | KCNK2KCNK10DHODHKMT2AHDAC1 | |
| SCHEMBL19554240 | 0.83 | STING1 (0.50) | KCNK2RAB9ADHODHKMT2ANPC1 | |
| SCHEMBL19554292 | 0.83 | PYGL (0.47) | KCNK2RAB9AKMT2ANPC1PYGL | |
| SCHEMBL19554206 | 0.82 | SLC16A3 (0.43) | KCNK2DHODHKMT2AACLYPYGL | |
| SCHEMBL19554338 | 0.82 | SLC16A3 (0.43) | KCNK2RAB9ADHODHKMT2ANPC1 | |
| SCHEMBL19554226 | 0.81 | KCNK2 (0.42) | KCNK2DHODHKMT2ASERPINE1ACLY | |
| SCHEMBL19554225 | 0.81 | SERPINE1 (0.43) | KCNK2DHODHKMT2ASERPINE1ACLY | |
| SCHEMBL19554278 | 0.81 | STING1 (0.43) | KCNK2DHODHKMT2ASERPINE1ACLY | |
| SCHEMBL19554093 | 0.81 | SMN1; SMN2 (0.62) | RAB9ACYP1A2CYP2C19KMT2ANPC1 | |
| SCHEMBL19554123 | 0.80 | KCNK2 (0.50) | KCNK2RAB9ACYP1A2CYP2C19KCNK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |