Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 2/20 | 0.43 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PYGL | P06737 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PRSS12 | P56730 | 3/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554338 | 0.91 | SLC16A3 (0.43) | SLC16A3KCNK2DHODHACLYMEN1 | |
| SCHEMBL19554145 | 0.87 | ALDH1A1 (0.45) | SLC16A3KCNK2DHODHMEN1PKM | |
| SCHEMBL19554330 | 0.86 | KCNK2 (0.46) | KCNK2DHODHACLYMEN1PKM | |
| SCHEMBL19554240 | 0.83 | STING1 (0.50) | KCNK2DHODHACLYMEN1PKM | |
| SCHEMBL19554173 | 0.82 | KCNK2 (0.48) | KCNK2DHODHACLYMEN1PKM | |
| SCHEMBL19555060 | 0.81 | MPO (0.41) | DHODHMEN1KMT2APYGLMAPT | |
| SCHEMBL19554296 | 0.81 | KCNK2 (0.40) | KCNK2DHODHMEN1PKMKMT2A | |
| SCHEMBL19554226 | 0.81 | KCNK2 (0.42) | KCNK2DHODHACLYMEN1PKM | |
| SCHEMBL19554225 | 0.81 | SERPINE1 (0.43) | KCNK2DHODHACLYMEN1PKM | |
| SCHEMBL19554093 | 0.81 | SMN1; SMN2 (0.62) | MEN1PKMKMT2APYGLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |