Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554330 | 0.95 | KCNK2 (0.46) | STING1ACLYKCNK2DHODHPRSS12 | |
| SCHEMBL19554123 | 0.90 | KCNK2 (0.50) | STING1ACLYKCNK2DHODHNPC1 | |
| SCHEMBL19554172 | 0.85 | DHODH (0.52) | ACLYDHODHNPC1PRSS12MEN1 | |
| SCHEMBL19575809 | 0.85 | KCNK2 (0.42) | ACLYKCNK2DHODHPRSS12MEN1 | |
| SCHEMBL19554229 | 0.84 | SERPINE1 (0.61) | KCNK2KDM4E | |
| SCHEMBL19554206 | 0.83 | SLC16A3 (0.43) | ACLYKCNK2DHODHPRSS12MEN1 | |
| SCHEMBL19554173 | 0.83 | KCNK2 (0.48) | ACLYKCNK2DHODHNPC1PRSS12 | |
| SCHEMBL19554338 | 0.83 | SLC16A3 (0.43) | ACLYKCNK2DHODHNPC1MEN1 | |
| SCHEMBL19554249 | 0.83 | ACLY (0.50) | ACLYDHODHPRSS12HDAC1MEN1 | |
| SCHEMBL19554225 | 0.82 | SERPINE1 (0.43) | ACLYKCNK2DHODHPRSS12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |