Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263634 | 0.85 | KIF11 (0.57) | PTPN11LMNACYP17A1CYP3A4HTT | |
| SCHEMBL264109 | 0.84 | CYP17A1 (0.50) | NOTUMPTPN11LMNACYP17A1CYP3A4 | |
| SCHEMBL69025 | 0.84 | PTPN11 (0.68) | PTPN11LMNAKDM4EHTTALDH1A1 | |
| SCHEMBL29365729 | 0.84 | PTPN11 (0.68) | PTPN11LMNAKDM4EHTTALDH1A1 | |
| SCHEMBL263146 | 0.83 | PTPN11 (0.54) | NOTUMPTPN11LMNACYP17A1CYP3A4 | |
| SCHEMBL385370 | 0.82 | LMNA (0.60) | NOTUMCFTRLMNAALDH1A1CA1 | |
| SCHEMBL8732524 | 0.82 | PTPN11 (0.66) | PTPN11LMNAKDM4EHTTALDH1A1 | |
| SCHEMBL11461692 | 0.81 | MAPT (0.43) | CFTRLMNACYP3A4KDM4EHTT | |
| SCHEMBL11744372 | 0.81 | PTPN11 (0.50) | NOTUMPTPN11CYP17A1CYP3A4KDM4E | |
| SCHEMBL10751302 | 0.81 | PTPN11 (0.50) | PTPN11CYP17A1CYP3A4KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |