Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554333 | 0.81 | AKR1C4 (0.56) | MAPTKDM4EKMT2AMEN1AKR1C4 | |
| SCHEMBL19554219 | 0.79 | AKR1C4 (0.48) | MAPTKDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL19554266 | 0.79 | KMT2A (0.55) | MAPTKDM4EKMT2AMEN1AKR1C4 | |
| SCHEMBL19554216 | 0.77 | AKR1C4 (0.46) | MAPTKDM4EKMT2AMEN1AKR1C4 | |
| SCHEMBL19554186 | 0.77 | MAPT (0.48) | MAPTKDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL420923 | 0.72 | SERPINE1 (0.61) | AKR1C4AKR1C3AKR1C2AKR1C1CA12 | |
| SCHEMBL21499320 | 0.70 | DHODH (0.77) | MAPTKDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7802430 | 0.69 | ROCK2 (0.58) | MAPTCYP3A4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6349877 | 0.69 | CHEK1 (0.66) | MAPTKDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL19554171 | 0.69 | PDE5A (0.48) | KMT2AMEN1AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |