Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.48 |
| ▸ | PDE1A | P54750 | 1/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554246 | 0.85 | PDE4B (0.44) | SERPINE1MEN1PKMKMT2ANPSR1 | |
| SCHEMBL19554415 | 0.85 | MEN1 (0.40) | MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL19554266 | 0.84 | KMT2A (0.55) | SERPINE1MEN1PKMKMT2ANPSR1 | |
| SCHEMBL19554253 | 0.84 | F11 (0.46) | SERPINE1MEN1PKMKMT2ANPSR1 | |
| SCHEMBL19554188 | 0.82 | F11 (0.47) | SERPINE1MEN1PKMKMT2ANPSR1 | |
| SCHEMBL19570245 | 0.82 | NPC1 (0.49) | SERPINE1MEN1PKMKMT2ANPSR1 | |
| SCHEMBL19554136 | 0.81 | MEN1 (0.48) | SERPINE1MEN1PKMKMT2ANPSR1 | |
| SCHEMBL19554158 | 0.80 | SLC16A3 (0.46) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL19554190 | 0.79 | KMT2A (0.49) | SERPINE1MEN1PKMKMT2ANPSR1 | |
| SCHEMBL19554194 | 0.79 | PDE5A (0.39) | PDE5APDE1APDE1BPDE1CAKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |