Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554177 | 0.95 | KCNK2 (0.44) | KCNK2DHODHKCNQ3KCNQ2KCNE1 | |
| SCHEMBL19575809 | 0.89 | KCNK2 (0.42) | KCNK2DHODHKCNQ3KCNQ2KCNE1 | |
| SCHEMBL19554185 | 0.89 | RAB9A (0.44) | KCNK2DHODHSLC16A3MEN1MAPT | |
| SCHEMBL19554123 | 0.86 | KCNK2 (0.50) | KCNK2DHODHKCNK10SLC16A3HDAC1 | |
| SCHEMBL19554226 | 0.86 | KCNK2 (0.42) | KCNK2DHODHKCNQ3KCNQ2KCNE1 | |
| SCHEMBL19554219 | 0.86 | AKR1C4 (0.48) | MEN1MAPTPKMKMT2ATDP1 | |
| SCHEMBL19554178 | 0.83 | NPC1 (0.52) | HDAC1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL19554335 | 0.82 | ALB (0.51) | KCNK2DHODHHDAC1MEN1MAPT | |
| SCHEMBL19554330 | 0.82 | KCNK2 (0.46) | KCNK2DHODHKCNK10HDAC1MEN1 | |
| SCHEMBL19554194 | 0.80 | PDE5A (0.39) | KCNK2DHODHSLC16A3NPC1AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |