Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | RARG | P13631 | 6/20 | 0.41 |
| ▸ | RARA | P10276 | 5/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554192 | 0.88 | KDM4E (0.61) | KDM4EPTPN1ALDH1A1HSD17B10TSHR | |
| SCHEMBL19554294 | 0.82 | NOTUM (0.51) | KDM4EALDH1A1MRGPRX4CA1CA2 | |
| SCHEMBL19554267 | 0.79 | KDM4E (0.62) | KDM4EPTPN1ALDH1A1HSD17B10TSHR | |
| SCHEMBL6916181 | 0.77 | KDM4E (0.68) | KDM4EPTPN1ALDH1A1HSD17B10TSHR | |
| SCHEMBL29359975 | 0.77 | KDM4E (0.68) | KDM4EPTPN1ALDH1A1HSD17B10TSHR | |
| SCHEMBL29594563 | 0.77 | KDM4E (0.68) | KDM4EPTPN1ALDH1A1HSD17B10TSHR | |
| SCHEMBL18758 | 0.77 | KDM4E (0.68) | KDM4EPTPN1ALDH1A1HSD17B10TSHR | |
| SCHEMBL8080613 | 0.76 | KDM4E (0.69) | KDM4EALDH1A1HPGD | |
| SCHEMBL18288105 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10TSHRRARB | |
| Terephthalic Acid SCHEMBL2846917 | 0.74 | TSHR (0.67) | KDM4EPTPN1ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |