Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554282 | 0.88 | KDM4E (0.59) | KDM4EPIM1AURKATPX2MRGPRX4 | |
| SCHEMBL2722609 | 0.83 | MRGPRX4 (0.55) | KDM4EPIM1MRGPRX4ALDH1A1GAA | |
| SCHEMBL219654 | 0.83 | EPHX2 (0.68) | AURKATPX2MRGPRX4EPHX2FAAH | |
| SCHEMBL17288697 | 0.81 | PIM1 (0.44) | KDM4EPIM1AURKATPX2EPHX2 | |
| Hydrochloric Acid SCHEMBL8086285 | 0.81 | EPHX2 (0.66) | AURKATPX2MRGPRX4EPHX2FAAH | |
| Hydrochloric Acid SCHEMBL10392412 | 0.81 | KDM4E (0.50) | KDM4EAURKATPX2MRGPRX4PTPN1 | |
| SCHEMBL29459930 | 0.80 | MRGPRX4 (0.61) | AURKATPX2MRGPRX4EPHX2GAA | |
| SCHEMBL496275 | 0.80 | MRGPRX4 (0.61) | AURKATPX2MRGPRX4EPHX2GAA | |
| SCHEMBL19554267 | 0.80 | KDM4E (0.62) | KDM4EMRGPRX4PTPN1ALDH1A1TSHR | |
| SCHEMBL29359975 | 0.78 | KDM4E (0.68) | KDM4EPTPN1ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |