Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 3/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 3/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018588 | 0.84 | KMT2A (0.64) | KDM4EMRGPRX4ALOX15GFERADAM17 | |
| Hydrochloric Acid SCHEMBL9015381 | 0.82 | KMT2A (0.62) | KDM4EMRGPRX4ALOX15GFERADAM17 | |
| SCHEMBL19554295 | 0.81 | PTPN11 (0.53) | KDM4EALOX15GFERADAM17ATM | |
| SCHEMBL16587854 | 0.81 | ALOX15 (0.47) | KDM4EALOX15GFERADAM17ATM | |
| SCHEMBL10081276 | 0.80 | KDM4E (0.66) | KDM4EKMT2AALDH1A1HSD17B10RARA | |
| SCHEMBL19554192 | 0.80 | KDM4E (0.61) | KDM4EMRGPRX4KMT2APTPN1TSHR | |
| SCHEMBL18758 | 0.79 | KDM4E (0.68) | KDM4EKMT2APTPN1TSHRMAPT | |
| SCHEMBL29359975 | 0.79 | KDM4E (0.68) | KDM4EKMT2APTPN1TSHRMAPT | |
| SCHEMBL29594563 | 0.79 | KDM4E (0.68) | KDM4EKMT2APTPN1TSHRMAPT | |
| SCHEMBL6916181 | 0.79 | KDM4E (0.68) | KDM4EKMT2APTPN1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |