Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554334 | 0.86 | KDM4E (0.53) | XDHALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6483619 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10KDM4EUSP2 | |
| SCHEMBL10801182 | 0.82 | TSHR (0.64) | ALDH1A1HPGDHSD17B10TSHRKDM4E | |
| SCHEMBL19554245 | 0.82 | XDH (0.48) | XDHMAP4K4 | |
| SCHEMBL23915464 | 0.81 | ALDH1A1 (0.44) | XDHALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL9862178 | 0.79 | ALDH1A1 (0.47) | XDHALDH1A1HPGDHSD17B10KDM4E | |
| Acetoacetic Acid SCHEMBL27837206 | 0.79 | XDH (0.41) | XDHALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL28025236 | 0.78 | TSHR (0.50) | ALDH1A1HPGDHSD17B10TSHRKDM4E | |
| SCHEMBL1730515 | 0.78 | TSHR (0.50) | XDHALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL11167484 | 0.77 | HSD17B10 (0.49) | ALDH1A1HPGDHSD17B10TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |