Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | NOS2 | P35228 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964399 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2AGFERNOS2RECQL | |
| SCHEMBL4947860 | 0.84 | ALOX15 (0.49) | SMN1; SMN2KMT2AGFERCYP3A4ALOX15 | |
| SCHEMBL17738062 | 0.82 | LMNA (0.47) | SMN1; SMN2KMT2AGFERCYP3A4ALOX15 | |
| SCHEMBL103642 | 0.82 | LMNA (0.47) | SMN1; SMN2KMT2AGFERCYP3A4ALOX15 | |
| SCHEMBL103641 | 0.82 | LMNA (0.47) | SMN1; SMN2KMT2AGFERCYP3A4ALOX15 | |
| SCHEMBL102768 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AGFERRECQLCYP3A4 | |
| SCHEMBL102769 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AGFERRECQLCYP3A4 | |
| SCHEMBL17737719 | 0.80 | USP2 (0.44) | SMN1; SMN2KMT2AGFERALOX15ALDH1A1 | |
| SCHEMBL17730420 | 0.80 | USP2 (0.44) | SMN1; SMN2KMT2AGFERALOX15ALDH1A1 | |
| SCHEMBL17730419 | 0.80 | USP2 (0.44) | SMN1; SMN2KMT2AGFERALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |