Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 8/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554350 | 0.91 | F2 (0.44) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL19554137 | 0.89 | ALDH1A1 (0.54) | MEN1KMT2APKMNPSR1NPC1 | |
| SCHEMBL19554170 | 0.85 | F2 (0.47) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL19554355 | 0.83 | DHODH (0.56) | NR1H4DHODHPRSS12MEN1KMT2A | |
| SCHEMBL19554323 | 0.81 | DHODH (0.68) | DHODHPRSS12MEN1KMT2APKM | |
| SCHEMBL19554338 | 0.80 | SLC16A3 (0.43) | DHODHMEN1KMT2APKMNPSR1 | |
| SCHEMBL19554348 | 0.79 | ALB (0.48) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL19554240 | 0.74 | STING1 (0.50) | DHODHPRSS12MEN1KMT2APKM | |
| SCHEMBL19554234 | 0.74 | DHODH (0.58) | NR1H4DHODHMEN1KMT2APKM | |
| SCHEMBL19554172 | 0.74 | DHODH (0.52) | NR1H4DHODHPRSS12MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |