Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | ADH5 | P11766 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12548095 | 0.90 | TBK1 (0.36) | TBK1ALDH1A1DHODHKMOALOX5 | |
| SCHEMBL19554684 | 0.88 | GRIK1 (0.34) | TBK1ALDH1A1DHODHKMOALOX5 | |
| SCHEMBL1947351 | 0.78 | DHODH (0.37) | TBK1ALDH1A1DHODHKMOALOX5 | |
| SCHEMBL19554929 | 0.78 | AKR1A1 (0.39) | TBK1KCNH2SLC6A2SLC6A4 | |
| SCHEMBL1948155 | 0.78 | TBK1 (0.37) | TBK1ALDH1A1DHODHKMOALOX5 | |
| SCHEMBL12548091 | 0.75 | ALDH1A1 (0.37) | TBK1ALDH1A1DHODHKMOALOX5 | |
| SCHEMBL23165627 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KMOALOX5RARBADH5 | |
| SCHEMBL29710171 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KMOALOX5RARBADH5 | |
| SCHEMBL6710242 | 0.74 | IDO1 (0.49) | TBK1ALDH1A1KMORARBGRIK1 | |
| SCHEMBL6530898 | 0.72 | ALDH1A1 (0.45) | TBK1ALDH1A1RARBFTOPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |