Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.49 |
| ▸ | IGF2R | P11717 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trehalose SCHEMBL23716930 | 0.92 | CD209 (0.44) | SLC7A5CD209IGF2RMAPTPTPN1 | |
| Maltose SCHEMBL8141523 | 0.89 | CD209 (0.51) | SLC7A5CD209IGF2RMEN1KMT2A | |
| SCHEMBL19555100 | 0.86 | CD209 (0.46) | CD209IGF2RPTPN1MEN1KMT2A | |
| Trehalose SCHEMBL9450109 | 0.86 | CD209 (0.46) | CD209IGF2RMAPTPTPN1L3MBTL1 | |
| SCHEMBL28329274 | 0.81 | HDAC3 (0.42) | CD209MAPTL3MBTL1PRKD3PRKCG | |
| Trehalose SCHEMBL20897335 | 0.80 | CD209 (0.42) | CD209IGF2RMAPTPTPN1 | |
| Trehalose SCHEMBL15510921 | 0.80 | KMT2A (0.51) | CD209IGF2RMAPTPTPN1MEN1 | |
| Trehalose SCHEMBL4636635 | 0.77 | IGF2R (0.56) | IGF2RMAPTPTPN1L3MBTL1MEN1 | |
| SCHEMBL23590699 | 0.77 | L3MBTL1 (0.47) | MAPTPTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL30852788 | 0.77 | CD209 (0.47) | CD209IGF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452170-A1 | DRY POWDER TREPROSTINIL FOR THE TREATMENT OF PULMONARY HYPERTENSION | Liquidia Technologies, Inc. (US) | 2019-03-13 | — | — | EP | disclosed |
| WO-2017192993-A1 | DRY POWDER TREPROSTINIL FOR THE TREATMENT OF PULMONARY HYPERTENSION | LIQUIDIA TECHNOLOGIES, INC. (US) | 2017-11-09 | — | — | WO | disclosed |