Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.46 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.44 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | IGF2R | P11717 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GJA1 | P17302 | 1/20 | 0.38 |
| ▸ | GJB2 | P29033 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17767394 | 0.86 | LGALS8 (0.49) | LGALS8SELEIGF2RMEN1KMT2A | |
| Trehalose SCHEMBL19555099 | 0.86 | SLC7A5 (0.50) | CD209IGF2RMEN1KMT2APRKD3 | |
| SCHEMBL8373863 | 0.85 | LGALS8 (0.48) | LGALS8SELEIGF2RMEN1KMT2A | |
| SCHEMBL12500790 | 0.81 | MAPK1 (0.41) | CD209LGALS8ALDH1A1 | |
| SCHEMBL7699917 | 0.80 | LGALS8 (0.42) | LGALS8SELEIGF2RMEN1KMT2A | |
| SCHEMBL7699916 | 0.80 | LGALS8 (0.42) | LGALS8SELEIGF2RMEN1KMT2A | |
| SCHEMBL1984503 | 0.79 | LGALS8 (0.52) | LGALS8SELEIGF2RMEN1KMT2A | |
| Maltose SCHEMBL8141523 | 0.79 | CD209 (0.51) | CD209LGALS8IGF2RMEN1KMT2A | |
| Trehalose SCHEMBL23716930 | 0.79 | CD209 (0.44) | CD209SELEIGF2RMEN1KMT2A | |
| SCHEMBL17767393 | 0.78 | IGF2R (0.44) | LGALS8IGF2RMEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452170-A1 | DRY POWDER TREPROSTINIL FOR THE TREATMENT OF PULMONARY HYPERTENSION | Liquidia Technologies, Inc. (US) | 2019-03-13 | — | — | EP | disclosed |
| WO-2017192993-A1 | DRY POWDER TREPROSTINIL FOR THE TREATMENT OF PULMONARY HYPERTENSION | LIQUIDIA TECHNOLOGIES, INC. (US) | 2017-11-09 | — | — | WO | disclosed |