SCHEMBL17767394

SCHEMBL17767394

CC(C)C(=O)O[C@@H]1[C@@H](O)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@H](CO)[C@H]1O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 6/20 0.49
▸ SELE P16581 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ PTPN1 P18031 1/20 0.42
▸ IGF2R P11717 1/20 0.41
▸ FGF1 P05230 1/20 0.41
▸ FGF2 P09038 1/20 0.41
▸ VEGFA P15692 1/20 0.41
▸ HPSE Q9Y251 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ TYR P14679 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7699917 0.93 LGALS8 (0.42) LGALS8SELEMEN1KMT2APTPN1
SCHEMBL7699916 0.93 LGALS8 (0.42) LGALS8SELEMEN1KMT2APTPN1
SCHEMBL17767393 0.92 IGF2R (0.44) LGALS8MEN1KMT2APTPN1IGF2R
SCHEMBL8373863 0.90 LGALS8 (0.48) LGALS8SELEMEN1KMT2APTPN1
SCHEMBL19555100 0.86 CD209 (0.46) LGALS8SELEMEN1KMT2APTPN1
SCHEMBL17767386 0.85 LGALS8 (0.46) LGALS8TYR
SCHEMBL8136408 0.85 L3MBTL1 (0.46) LGALS8L3MBTL1TYR
SCHEMBL12290512 0.85 L3MBTL1 (0.46) LGALS8L3MBTL1TYR
SCHEMBL8069003 0.85 L3MBTL1 (0.46) LGALS8L3MBTL1TYR
SCHEMBL27654959 0.85 L3MBTL1 (0.46) LGALS8L3MBTL1TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115501172-A Gel formulations for topical drug delivery 丹麦技术大学 2022-12-23 — — CN disclosed
CN-107249570-B Gel formulations for topical drug delivery 丹麦技术大学 2022-08-09 — — CN disclosed
US-20210386669-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2021-12-16 — — US disclosed
US-11065201-B2 Gel formulations for local drug release TECHNICAL UNIVERSITY OF DENMARK (DK) 2021-07-20 — — US disclosed
US-11058780-B2 Palpable marker composition TECHNICAL UNIVERSITY OF DENMARK (DK) 2021-07-13 — — US disclosed
US-20190275174-A1 PALPABLE MARKER COMPOSITION TECHNICAL UNIVERSITY OF DENMARK (DK) 2019-09-12 — — US disclosed
EP-3458029-A1 PALPABLE MARKER COMPOSITION Technical University of Denmark (DK) 2019-03-27 — — EP disclosed
CN-109475491-A Palpable marker compositions 丹麦技术大学 2019-03-15 — — CN disclosed
US-20180325819-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2018-11-15 — — US disclosed
WO-2017198858-A1 PALPABLE MARKER COMPOSITION TECHNICAL UNIVERSITY OF DENMARK (DK) 2017-11-23 — — WO disclosed
CN-107249570-A Gel formulations for topical drug delivery 丹麦技术大学 2017-10-13 — — CN disclosed
EP-3220887-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE Technical University of Denmark (DK) 2017-09-27 — — EP disclosed
WO-2016079330-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2016-05-26 — — WO disclosed
WO-2016079331-A1 GEL FORMULATIONS FOR ENHANCING THE EFFECT OF RADIOTHERAPY TECHNICAL UNIVERSITY OF DENMARK (DK) 2016-05-26 — — WO disclosed
WO-2016079332-A1 GEL FORMULATIONS FOR IMPROVING IMMUNOTHERAPY TECHNICAL UNIVERSITY OF DENMARK (DK) 2016-05-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190275174-A1 PALPABLE MARKER COMPOSITION TREH, LGALS8, PYGM LGALS8 2/4885SELE 1828/4885MEN1 3511/4885
US-11065201-B2 Gel formulations for local drug release TREH, GALE, SLC2A8 LGALS8 19/4885SELE 1969/4885MEN1 4426/4885
US-11058780-B2 Palpable marker composition TREH, LGALS8, PYGM LGALS8 2/4885SELE 1828/4885MEN1 3511/4885
US-20180325819-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TREH, GALE, SLC2A8 LGALS8 19/4885SELE 1969/4885MEN1 4426/4885
US-20210386669-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TREH, GALE, SLC2A8 LGALS8 19/4885SELE 1969/4885MEN1 4426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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