Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.40 |
| ▸ | MAOB | P27338 | 11/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18634514 | 0.81 | ATM (0.41) | MAOAMAOBHSD17B1PRKCIMEN1 | |
| SCHEMBL17332111 | 0.81 | PRF1 (0.46) | MEN1MAPK1KMT2ABAZ2B | |
| SCHEMBL14013915 | 0.81 | MAOA (0.56) | MAOAMAOBHSD17B1PRKCIBAZ2B | |
| SCHEMBL6122076 | 0.81 | MAOB (0.44) | MAOAMAOBHSD17B1PRKCIMEN1 | |
| SCHEMBL17332134 | 0.81 | MAOA (0.42) | MAOAMAOBHSD17B1PRKCIMEN1 | |
| SCHEMBL17332146 | 0.81 | MAOB (0.42) | MAOAMAOBHSD17B1PRKCIMEN1 | |
| SCHEMBL7507446 | 0.79 | MAOA (0.53) | MAOAMAOBHSD17B1PRKCIMAPK1 | |
| SCHEMBL17332107 | 0.79 | LMNA (0.40) | MAOAMAOBHSD17B1PRKCIMEN1 | |
| SCHEMBL14966534 | 0.79 | BAZ2B (0.46) | MAOAMAOBHSD17B1PRKCIMEN1 | |
| SCHEMBL17332076 | 0.79 | ROCK2 (0.44) | MAOAMAOBPRKCIMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809600-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2017-11-07 | — | — | US | disclosed |
| US-9809600-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2017-11-07 | — | — | US | disclosed |