Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12278913 | 0.76 | — | — | |
| SCHEMBL22502897 | 0.74 | ALKBH5 (0.38) | MEN1NPC1HCRTR1RAB9AKMT2A | |
| SCHEMBL30444626 | 0.74 | KMT2A (0.46) | MEN1KMT2AKDM4EALDH1A1ADRA2A | |
| SCHEMBL29509065 | 0.73 | ALKBH5 (0.42) | KMT2ATLR8ALKBH5FTOCYP1A2 | |
| SCHEMBL17504843 | 0.73 | ALKBH5 (0.42) | KMT2ATLR8ALKBH5FTOCYP1A2 | |
| SCHEMBL1092872 | 0.72 | ALKBH5 (0.42) | MEN1NPC1HCRTR1RAB9AKMT2A | |
| SCHEMBL19557287 | 0.70 | KDM4E (0.36) | MEN1KMT2ACYP1A2KDM4EALDH1A1 | |
| SCHEMBL15639395 | 0.70 | ATM (0.38) | MEN1NPC1RAB9AKMT2ACYP1A2 | |
| SCHEMBL19559062 | 0.70 | ALKBH5 (0.35) | MEN1NPC1HCRTR1RAB9AKMT2A | |
| SCHEMBL3229629 | 0.70 | TAAR1 (0.39) | MEN1NPC1HCRTR1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380943-A1 | METHOD FOR THE SILYLATION OF A C-H BOND WITH A SILYLATED DIAZENE | SORBONNE UNIVERSITE (FR) | 2024-06-12 | — | — | EP | disclosed |
| US-11753421-B2 | Silylated derivatives of aromatic heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753421-B2 | Silylated derivatives of aromatic heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-09-12 | — | — | US | disclosed |
| CN-111253424-B | Silylation of aromatic heterocycles over earth-rich transition metal-free catalysts | 加州理工学院 | 2023-06-20 | — | — | CN | disclosed |
| EP-3705482-B1 | SILYLATION OF AROMATIC HETEROCYCLES BY EARTH ABUNDANT TRANSITION-METAL-FREE CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2023-02-22 | — | — | EP | disclosed |
| WO-2023012494-A1 | METHOD FOR THE SILYLATION OF A C-H BOND WITH A SILYLATED DIAZENE | SORBONNE UNIVERSITE (FR) | 2023-02-09 | — | — | WO | disclosed |
| US-20220185828-A1 | Silylated Derivatives Of Aromatic Heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2022-06-16 | — | — | US | disclosed |
| US-11312733-B2 | Silylated derivatives of aromatic heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-04-26 | — | — | US | disclosed |
| CN-111253424-A | Silylation of aromatic heterocycles by earth-rich transition metal-free catalysts | 加州理工学院 | 2020-06-09 | — | — | CN | disclosed |
| CN-107108662-B9 | Silylation of aromatic heterocycles by earth-rich transition metal-free catalysts | 加州理工学院 | 2020-05-15 | — | — | CN | disclosed |
| CN-107108662-B | Silylation of aromatic heterocycles by earth-rich transition metal-free catalysts | 加州理工学院 | 2020-02-07 | — | — | CN | disclosed |
| US-20180057514-A1 | SILYLATION OF AROMATIC HETEROCYCLES BY EARTH ABUNDANT TRANSITION-METAL-FREE CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2018-03-01 | — | — | US | disclosed |
| US-9809607-B2 | Silylation of aromatic heterocycles by earth abundant transition-metal-free catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312733-B2 | Silylated derivatives of aromatic heterocycles | KCNH1, KCNH3, HNRNPH3 | MEN1 3045/4885NPC1 1172/4885HCRTR1 4471/4885 |
| US-20180057514-A1 | SILYLATION OF AROMATIC HETEROCYCLES BY EARTH ABUNDANT TRANSITION-METAL-FREE CATALYSTS | TEC, AURKA, TYR | MEN1 806/4885NPC1 1990/4885HCRTR1 4821/4885 |
| US-11753421-B2 | Silylated derivatives of aromatic heterocycles | KCNH1, KCNH3, HNRNPH3 | MEN1 3045/4885NPC1 1172/4885HCRTR1 4471/4885 |
| US-20220185828-A1 | Silylated Derivatives Of Aromatic Heterocycles | KCNH1, KCNH3, HNRNPH3 | MEN1 3045/4885NPC1 1172/4885HCRTR1 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.