SCHEMBL19558265

CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)C(C)C

nearest known ligand 0.55

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	FURIN	P09958	2/20	0.55

▸	PCSK6	P29122	1/20	0.55

▸	NPY4R	P50391	14/20	0.51

▸	NPY1R	P25929	9/20	0.51

▸	NPY5R	Q15761	9/20	0.51

▸	NPY2R	P49146	6/20	0.51

▸	TFPI	P10646	1/20	0.49

▸	SIRT5	Q9NXA8	1/20	0.47

▸	SIRT6	Q8N6T7	1/20	0.46

▸	SIRT1	Q96EB6	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15896438	1.00	FURIN (0.55)	FURINPCSK6NPY4RNPY1RNPY5R
SCHEMBL15185942	0.90	NPY4R (0.56)	NPY4RNPY1RNPY5RNPY2RSIRT6
SCHEMBL10169080	0.89	NPY4R (0.54)	NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL15185926	0.89	TFPI (0.57)	FURINTFPI
SCHEMBL16189767	0.88	TLR2 (0.48)	FURINPCSK6NPY4RNPY1RNPY5R
SCHEMBL20439438	0.88	TLR2 (0.48)	FURINPCSK6NPY4RNPY1RNPY5R
SCHEMBL16181239	0.88	SIRT6 (0.57)	FURINPCSK6NPY4RNPY1RNPY5R
SCHEMBL31024641	0.87	SIRT6 (0.57)	NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL29626768	0.87	SIRT6 (0.57)	NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL27852310	0.87	NPY4R (0.57)	NPY4RNPY1RNPY5RNPY2RSIRT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9809621-B2	Stable peptide-based PACE4 inhibitors	SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA)	2017-11-07	—	—	US	disclosed