SCHEMBL29626768

SCHEMBL29626768

CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIRT6 Q8N6T7 1/20 0.57
SIRT1 Q96EB6 1/20 0.57
SIRT5 Q9NXA8 2/20 0.55
NPY4R P50391 10/20 0.47
NPY1R P25929 7/20 0.47
NPY2R P49146 6/20 0.47
NPY5R Q15761 6/20 0.47
TLR2 O60603 2/20 0.46
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
ROCK2 O75116 2/20 0.43
PRKACA P17612 1/20 0.43
AKT3 Q9Y243 1/20 0.43
ALB P02768 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31024641 1.00 SIRT6 (0.57) SIRT6SIRT1SIRT5NPY4RNPY1R
SCHEMBL15987249 0.93 SIRT5 (0.57) SIRT6SIRT1SIRT5NPY4RNPY1R
SCHEMBL16045801 0.93 SIRT5 (0.57) SIRT6SIRT1SIRT5NPY4RNPY1R
SCHEMBL29397145 0.91 SIRT6 (0.56) SIRT6SIRT1SIRT5NPY4RNPY1R
SCHEMBL29396582 0.91 SIRT6 (0.56) SIRT6SIRT1SIRT5NPY4RNPY1R
SCHEMBL29396719 0.91 SIRT6 (0.56) SIRT6SIRT1SIRT5NPY4RNPY1R
SCHEMBL23335231 0.89 SIRT6 (0.47) SIRT6SIRT1SIRT5NPY4RNPY1R
SCHEMBL15185942 0.89 NPY4R (0.56) SIRT6SIRT1NPY4RNPY1RNPY2R
SCHEMBL10169080 0.88 NPY4R (0.54) SIRT6SIRT1NPY4RNPY1RNPY2R
SCHEMBL24900018 0.88 SIRT5 (0.49) SIRT6SIRT1SIRT5NPY4RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2367852-B1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS SEDERMA SA (FR) 2023-08-30 EP disclosed
EP-3744729-B1 PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMOPHARMACEUTICAL USES SEDERMA SA (FR) 2023-03-01 EP disclosed
US-11331305-B2 Peptides for skin rejuvenation and methods of using the same ANTEIS SA (CH) 2022-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11331305-B2 Peptides for skin rejuvenation and methods of using the same CUTA, PLOD3, MMP13 SIRT6 644/4885SIRT1 273/4885SIRT5 973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.