Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | NMT2 | O60551 | 1/20 | 0.47 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | TFPI | P10646 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.43 |
| ▸ | NPY4R | P50391 | 4/20 | 0.42 |
| ▸ | NPY1R | P25929 | 3/20 | 0.42 |
| ▸ | NPY2R | P49146 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 2/20 | 0.42 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16189767 | 1.00 | TLR2 (0.48) | TLR2NMT2NMT1TFPISIRT5 | |
| SCHEMBL20439410 | 0.99 | TLR2 (0.49) | TLR2NMT2NMT1TFPISIRT5 | |
| SCHEMBL20439464 | 0.95 | SIRT5 (0.51) | TLR2NMT2NMT1TFPISIRT5 | |
| Cn-105 SCHEMBL20439448 | 0.95 | SIRT5 (0.47) | TLR2NMT2NMT1TFPISIRT5 | |
| Cn-105 SCHEMBL16189774 | 0.95 | SIRT5 (0.47) | TLR2NMT2NMT1TFPISIRT5 | |
| SCHEMBL16189768 | 0.93 | NMT2 (0.46) | TLR2NMT2NMT1TFPISIRT5 | |
| SCHEMBL20439451 | 0.92 | SIRT6 (0.46) | TLR2NMT2NMT1TFPISIRT5 | |
| SCHEMBL20439409 | 0.92 | NMT1 (0.48) | TLR2NMT2NMT1TFPISIRT5 | |
| SCHEMBL19558265 | 0.88 | FURIN (0.55) | TFPISIRT5SIRT6SIRT1NPY4R | |
| SCHEMBL15896438 | 0.88 | FURIN (0.55) | TFPISIRT5SIRT6SIRT1NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136371-B2 | Peptide compounds for suppressing inflammation | DUKE UNIVERSITY (US) | 2021-10-05 | — | — | US | disclosed |
| US-20190194296-A1 | PEPTIDE COMPOUNDS FOR SUPPRESSING INFLAMMATION | UNIV DUKE (US) | 2019-06-27 | — | — | US | disclosed |
| WO-2018140563-A1 | USE OF APOE MIMETIC PEPTIDES FOR REDUCING THE LIKELIHOOD OF EPILEPTOGENESIS | DUKE UNIVERSITY (US) | 2018-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136371-B2 | Peptide compounds for suppressing inflammation | APOB, IAPP, CCL2 | TLR2 305/4885NMT2 1841/4885NMT1 2064/4885 |
| US-20190194296-A1 | PEPTIDE COMPOUNDS FOR SUPPRESSING INFLAMMATION | APOB, IAPP, CCL2 | TLR2 305/4885NMT2 1841/4885NMT1 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.