Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 11/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748863 | 1.00 | FPR2 (0.47) | FPR2AAK1LMNAGAAMAPT | |
| SCHEMBL19563215 | 0.89 | FPR2 (0.41) | FPR2AAK1GAAMAPTSMN1; SMN2 | |
| SCHEMBL16748862 | 0.88 | FPR2 (0.48) | FPR2AAK1LMNAGAAMAPT | |
| SCHEMBL19563473 | 0.87 | FPR2 (0.44) | FPR2LMNAMAPTMEN1KMT2A | |
| SCHEMBL16748921 | 0.87 | FPR2 (0.44) | FPR2LMNAMAPTMEN1KMT2A | |
| SCHEMBL16742481 | 0.86 | FPR2 (0.47) | FPR2MEN1KMT2A | |
| SCHEMBL19563289 | 0.86 | FPR2 (0.47) | FPR2MEN1KMT2A | |
| SCHEMBL16748772 | 0.85 | FPR2 (0.46) | FPR2AAK1LMNAGAAMAPT | |
| SCHEMBL19563339 | 0.85 | FPR2 (0.46) | FPR2AAK1LMNAGAAMAPT | |
| SCHEMBL16748816 | 0.84 | MEN1 (0.50) | FPR2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071548-B1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2017-11-08 | — | — | EP | disclosed |